PANGOLINS LACK IFIH1/MDA5, A CYTOPLASMIC RNA SENSOR THAT INITIATES INNATE IMMUNE DEFENSE UPON CORONAVIRUS INFECTION

Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection

Zoonotic infections are an imminent threat to human health.Pangolins were recently identified as carriers and intermediate hosts of coronaviruses.Previous research has shown that infection with coronaviruses activates an innate immune response upon sensing of viral RNA by interferon-induced with helicase C domain 1 (IFIH1), also known as MDA5.Here,

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A street-level assessment of greenhouse gas emissions associated with traffic congestion in the city of Nairobi, Kenya

Traffic congestion significantly contributes to climate change due to the emissions of Greenhouse Gases (GHGs) such as Carbon Dioxide (CO2), Nitrous Oxide (N2O), and Ozone (O3).Rapid urbanization and poor planning coupled with increased motorization and fragmented public transport system low profile barn door kit in cities such as Nairobi have led

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Associations between exposure to potentially psychologically traumatic events and mental ill health among New Zealand firefighters: A cross-sectional study

Background: Fire and emergency services personnel face unique occupational hazards, including repeated exposure to potentially psychologically traumatic events (PPTEs), which can impact their mental health.Despite growing awareness, comprehensive data on the mental health of fire and emergency services personnel in New Zealand remains sparse.Purpos

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